Makoto Sainouchi

Highly qualified neurologist experienced in diagnosing and treating acute and chronic diseases. Over 4 years specializing in neurological conditions affecting elderly populations including neurodegenerative disease, and neurological disorders of the elderly including stroke and epilepsy. 4 years studying the pathology of neurodegenerative diseases through autopsies and received Ph.D. In addition to his clinical practice, currently energetically writing papers and presenting them at conferences. Board-certified in neurology from Japanese society of neurology.

Board-certified in Neurology

• Sainouchi M, Tada M, Fitrah YA, Hara N, Tanaka K, Idezuka J, Aida I, Nakajima T, Miyashita A, Akazawa K, Ikeuchi T, Onodera O, Kakita A. Brain TDP-43 pathology in corticobasal degeneration: topographical correlation with neuronal loss. Neuropathol Appl Neurobiol. 2022, 48: e12786.
• Sainouchi M, Tanaka H, Shimizu H, Mashima T, Fukushima T, Hatano Y, Ishihara T, Makino K, Onodera O, Kakita A. Hemiplegic-type ALS: clinicopathological features of two autopsied patients. J Neurol Neurosurg Psychiatry. 2021, 92:1014-1016.
• Sainouchi M, Hatano Y, Tada M, Ishihara T, Ando S, Kato T, Tokunaga J, Ito G, Miyahara H, Toyoshima Y, Yokoseki A, Ozawa T, Akazawa K, Onodera O, Kakita A. A novel splicing variant of ANXA11 in a patient with amyotrophic lateral sclerosis: histologic and biochemical features. Acta Neuropathol Commun. 2021, 9:106.
• Zhou Y, Song WM, Andhey PS, Swain A, Levy T, Miller KR, Poliani PL, Cominelli M, Grover S, Gilfillan S, Cella M, Ulland TK, Zaitsev K, Miyashita A, Ikeuchi T, Sainouchi M, Kakita A, Bennett DA, Schneider JA, Nichols MR, Beausoleil SA, Ulrich JD, Holtzman DM, Artyomov MN, Colonna M. Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease. Nat Med. 2020, 26:131-142.
• Sainouchi M, Nakamura M, Masuda Y, Ohtani R. A case of oculomotor disorder and urinary retention due to a lower midbrain lesion. Clinical Neurology. 2021, 93:305-309
• Kunii Y, Matsumoto J, Izumi R, Nagaoka A, Hino M, Shishido R, Sainouchi M, Akatsu H, Hashizume Y, Kakita A, Yabe H. Evidence for Altered Phosphoinositide Signaling-Associated Molecules in the Postmortem Prefrontal Cortex of Patients with Schizophrenia. Int J Mol Sci. 2021, 22:8280.
• Izumi R, Hino M, Wada A, Nagaoka A, Kawamura T, Mori T, Sainouchi M, Kakita A, Kasai K, Kunii Y, Yabe H. Detailed Postmortem Profiling of Inflammatory Mediators Expression Revealed Post-inflammatory Alternation in the Superior Temporal Gyrus of Schizophrenia. Front Psychiatry. 2021, 12:653821.
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