David Bierbrauer

• Project: Sensitivity to social contingency of the mouse hippocampus
• Development of a novel behavioral task for mice in an automated test system to investigate the functionality of the hippocampus in social memory

• Project: High-throughput automated home-cage mesoscopic functional imaging of mouse cortex
• Publication: https://elifesciences.org/articles/55964
• Development and maintenance of an inexpensive automated voluntary head-fixing system for mice for high-throughput brain imaging
• Implementation of a MySQL database and computational pipelining of large-scale data analysis and graphical display

Thesis project: Implementation of an Artificial Neural Network for the purpose of estimating parameters and kinetics of experimental data

• Training of an Artificial Neural Network with theoretical and modeled data
• The trained DNN should distinguish between different kinetics, estimate reaction rates of experimental data in systems biology, and, if possible, make predictions of the underlying pathway
• The main goal was to specify criteria for experimental data for efficient modelling

• Master student - Research project
• Development of an automated training system for the investigation of dendritic activity after memory formation
• Development and construction of an automated homecage system for training mice to react to a specific somatosensory stimulus
• Automatic storage of data in a MySQL database and development of a website with tools for observation and data analysis

• Teaching students of the Biophysics bachelor’s program in mathematics and physics.

• Thesis project: Properties of spikelets generated via electrotonic coupling
• Implementation of a theoretical model to simulate whether fast spikelets in pyramidal neurons can have their origin in gap junctions
• Experimental in vivo data were provided by the lab of Michael Brecht