A.S.M. Sakhawat Hossain

Highly analytical and adaptable professional with excellent communication and teamwork skills. Proven ability to quickly adapt to new environments and contribute to team success. Committed to continuously developing professional skills and maintaining a positive attitude. Dedicated to ongoing learning and growth.

• Date of Birth: 03/26/89
• Place of Birth: Rajshahi-6204, Bangladesh
• Nationality: Bangladeshi
• Gender: Male

Apoptogenic effect of antioxidative fraction of Morus alba stem bark on EAC cells induced tumor-bearing Swiss albino mice.

• 10/2021 - present, Ph.D. student studying the molecular mechanism of a tight skin phenotype caused by a novel fibrillin-1 mutation under Professor Hiromi Yanagisawa at TARA, University of Tsukuba.
• 02/02/2016 - 08/31/2021, Supervised undergraduate student projects in the Dept. of Pharmacy, Varendra University, Bangladesh.
• 10/01/2013 - 05/15/2014, Worked as a research assistant in the Molecular Pharmacology Lab, Dept. of Pharmacy, University of Rajshahi, collaborating with BCSIR to study the antioxidant and anticancer properties of vegetables grown in Bangladesh.
• 10/01/2012 - 09/30/2013, Completed a one-year master’s thesis in the Molecular Pharmacology Laboratory, Dept. of Pharmacy, University of Rajshahi, focusing on in vitro antioxidant and in vivo anticancer experiments in a mice model.

• Immunohistochemistry
• Western blot
• qPCR
• RNA isolation and purification
• Dermal fibroblast isolation
• Cell culture
• Biomechanical and biological assays
• Mice handling techniques
• Manuscript writting
• SPSS
• ImageJ
• Prism

• The Antioxidative Fraction of White Mulberry Induces Apoptosis through Regulation of p53 and NFκB in EAC Cells, PLoS ONE, 2016, ASM Sakhawat Hossain, AHM Khurshid Alam, Muhammad Ali Khan, Syed Rashel Kabir, Md Abu Reza, Md Mahbubur Rahman, Mohammad Saiful Islam, Md Aziz Abdur Rahman, Mamunur Rashid, Md Golam Sadik
• Evaluation of antioxidant and anticancer properties of the seed extracts of Syzygium fruticosum Roxb. growing in Rajshahi, Bangladesh, BMC Complementary and Alternative Medicine, 2013, Shafiqul Islam, Samima Nasrin, Muhammad Ali Khan, ASM Sakhawat Hossain, Farhadul Islam, Proma Khandokhar, M Nurul Haque Mollah, Mamunur Rashid, Golam Sadik, Md Aziz Abdur Rahman, AHM Khurshid Alam
• Evaluation of anti-ROS and anticancer properties of Tabebuia pallida L. Leaves, Clinical Phytoscience, 2019, Md Mahbubur Rahman, A.S.M. Sakhawat Hossain, Md. Golam Mostofa, Muhammad Ali Khan, Rezwan Ali, Ashik Mosaddik, Md. Golam Sadik, A.H.M. Khurshid Alam
• Comparative evaluation of the antimicrobial activity of different parts of Abelmoschus moschatus against multi-resistant pathogens, International Journal of Pharmaceutical Sciences and Research, 2017, M. M. Rahman, M. N. Haque, S. Hosen, J. Akhter, U.S.B. Kamal, E. N. Jahan, ASM S. Hossain, M. N. Uddin, M. B. Islam, M. R. Islam, AHM K. Alam, A. Mosaddik
• Phytochemical and Antimicrobial properties of Tiliacora triandra stem bark, British Journal of Pharmaceutical Research, 2017, Md. Mahbubur Rahman, Md. Shamsuzzaman, Mahfuza Khatun, Md. Mostafijur Rahman, A.S.M. Sakhawat Hossain, A. H. M. Khurshid Alam, Ashik Mosaddik, Mir Imam Ibne Wahed
• The Plant Aerva sanguinolenta: A Review on Traditional uses, Phytoconstituents and Pharmacological Activities, Pharmacogn Rev, 2019, Joy Sarker, Md. Rahmat Ali, Muhammad Ali Khan, Md. Mahbubur Rahman, ASM Sakhawat Hossain, AHM Khurshid Alam

• Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice, 56th Annual Meeting of the Japan Connective Tissue Society
• A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes an Abnormal Skin Phenotype, Tissue, Matrix, and Pathobiology: A joint meeting of the ASMB, HCS, and ASIP
• Investigating the skin phenotype caused by a novel mutation in the hybrid 1 domain of fibrillin 1 gene, International Symposium on Skin Stem Cell Dynamics
• The potential role of Fibulin 7 in skin inflammatory disease psoriasis, International Symposium on Skin Stem Cell Dynamics
• Investigating the molecular mechanism of stiff skin-like phenotype in a mouse model caused by a new point mutation in the hybrid domain of fibrillin 1 (Fbn1) gene, Tsukuba Global Science Week
• Apoptogenic effect of antioxidant-enriched leaves of Tabebuia pallida in EAC cells, International Conference on “Ethnopharmacology & Drug Development: Innovation Meets Tradition”
• Antioxidant and Anticancer Properties of Tabebuia pallida L. Leaves, International Conference on “Ethnopharmacology & Drug Development: Innovation Meets Tradition”
• A comparative investigation to evaluate the analgesic, anti-inflammatory, and CNS depressant activities of different parts of Solanum indicum in mice, Conference on Material Science and Nano-Electrochemistry-2017
• Cytotoxic and Apoptogenic Effect of Tabebuia pallida on Ehrlich Ascites Carcinoma Cells, International Conference on Bioinformatics and Biostatistics for Agriculture, Health and Environment” 2017
• Polyphenolic contents and antioxidant potential of stem bark extracts from Morus alba L. (Moraceae), Bangladesh Society for Biochemistry and Molecular Biology Conference

• The 56th Annual Meeting of the Japan Connective Tissue Society, University of Tsukuba, Japan, 06/15/2024 - 06/16/2024.
• Tissue, Matrix, and Pathobiology: A joint meeting of the American Society for Matrix Biology (ASMB), the Histochemical Society (HCS), and the American Society for Investigative Pathology (ASIP), Salt Lake City, Utah, USA, 10/22/2023 - 10/25/2023.
• International Symposium on Skin Stem Cell Dynamics, University of Tokyo, Japan, 05/14/2023 - 05/15/2023.
• Tsukuba Global Science Week, University of Tsukuba, Japan, 09/25/2022 - 09/30/2022.
• Conference on Material Science and Nano-Electrochemistry (CMSN-2017), University of Rajshahi, Bangladesh.
• International Conference on Bioinformatics and Biostatistics for Agriculture, Health and Environment” 2017, University of Rajshahi, Bangladesh.
• BSBMB conference, 2013 on “Biochemistry and Molecular Biology for Better Health, Congenial Environment and Food Security”, University of Chittagong, Bangladesh.

• Awarded the MEXT 2020 Fellowship from the Ministry of Education, Culture, Sports, Science and Technology of Japan for a 4-year Ph.D. program in medical science at the University of Tsukuba.
• Received the NST Fellowship for 2013-14, funded by the Ministry of Science and Technology (MOST), Government of Bangladesh.
• Awarded Bangladesh Education Board scholarships at various school and college levels for academic excellence.
• Honored with the Mayor Award from the City Corporation of Rajshahi, Bangladesh, in 2006 and 2004 for outstanding achievements in the Higher Secondary Certificate and Secondary School Certificate examinations, respectively.

• Hiromi Yanagisawa, Director and Professor, Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan, Email: hkyanagisawa@tara.tsukuba.ac.jp
• Erna Raja, Assistant Professor, Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan, Email: rajaerna@tara.tsukuba.ac.jp